Early Orchiopexy to Prevent Germ Cell Loss during Infancy in Congenital Cryptorchidism
نویسندگان
چکیده
منابع مشابه
The epidemiology of congenital cryptorchidism, testicular ascent and orchiopexy.
PURPOSE The frequency, significance and possible etiology of testicular ascent (acquired cryptorchidism) are characterized in light of the known incidence and natural history of congenital cryptorchidism, and data provided by longitudinal and epidemiological studies of ascended testes and orchiopexy rates. MATERIALS AND METHODS We comprehensively reviewed the literature addressing the epidemi...
متن کاملEarly orchiopexy: prepubertal intratubular germ cell neoplasia and fertility outcome.
OBJECTIVES To investigate the prepubertal prevalence of intratubular germ cell neoplasia of the unclassified type (ITGCNU) and its significance as a predictor of testicular cancer and to evaluate the effect of early orchiopexy (at younger than 2 years of age) on subsequent fertility of patients with bilateral cryptorchidism. METHODS Testicular biopsies (n = 660) from 440 prepubertal patients ...
متن کاملGerm cell development in the postnatal testis: the key to prevent malignancy in cryptorchidism?
To permit normal postnatal germ cell development, the mammalian testis undergoes a complex, multi-staged process of descent to the scrotum. Failure of any part of this process leads to congenital cryptorchidism, wherein the malpositioned testis finds itself at the wrong temperature after birth, which leads to secondary germ cell loss and later infertility and risk of cancer. Recent studies sugg...
متن کاملCryptorchidism with short spermatic vessels: staged orchiopexy preserving spermatic vessels.
PURPOSE Patients with cryptorchidism can have such short spermatic vessels that it is impossible to place the testicle in a satisfactory scrotal position using conventional orchiopexy. In these cases the most commonly used operation is 1 to 2-stage Fowler-Stephens orchiopexy. We present our surgical experience using staged inguinal orchiopexy without section of the spermatic vessels in patients...
متن کاملStrategies to Prevent Germ Cell Death for Fertility Preservation
................................................................................................................................. 8 INTRODUCTION....................................................................................................................... 10 REVIEW OF LITERATURE..................................................................................................... 13 APOPT...
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ژورنال
عنوان ژورنال: The Journal of Clinical Endocrinology & Metabolism
سال: 2012
ISSN: 0021-972X,1945-7197
DOI: 10.1210/jc.2012-3662